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Case Study: Lifecycle Management Services

2013-03-06 12:09:26| drugdiscoveryonline Downloads

A marketed adult tablet was reported to have an extremely bad taste and after taste. The customer came to Patheon for taste masking to improve patient compliance, and explore line extension into the pediatric market.

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Case Study: Molecular Structure Analysis

2013-03-06 11:34:54| drugdiscoveryonline Downloads

A new degradation product was observed in accelerated stability chromatograms for a new formulation. A tentative structural assignment was made by the customer’s consultant but needed to be verified.

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Case Study: Taking Formulations To The Next Level

2013-03-06 11:32:41| drugdiscoveryonline Downloads

The Challenge: Transfer a manufacturing process from a client/CMO site, and propose improvements to formulation.

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Case Study: Formulation Development For Complex APIs And Dose Forms

2013-03-06 11:30:00| drugdiscoveryonline Downloads

A large pharmaceutical company contracted Patheon to develop a bilayer tablet, each layer consisting of a different drug substance and release profile. One of the drugs was low dose and moisture sensitive. There were also layer lamination issues during formulation development and in storage.

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Case Study: Excipient Compatibility Testing

2013-03-06 11:19:45| drugdiscoveryonline Downloads

A customer came to Patheon with a new molecule that’s chemical structure indicated potential for oxidative degradation and hydrolysis. Their goal was to develop a solid oral dosage form that overcame these stability issues.

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