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Merck Announces Positive Study Investigating the Use of KEYTRUDA (pembrolizumab) Compared to Chemotherapy in Patients with Ipilimumab-Refractory Advanced Melanoma

2014-11-16 10:25:00| Merck.com - Research & Development News

Dateline City: ZURICH KEYTRUDA Demonstrated Superiority to Chemotherapy for Primary Endpoint of Progression-Free Survival Findings Presented for First Time at Society of Melanoma Research (SMR) 2014 International Congress ZURICH--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, announced today that a pre-specified analysis of investigational data from a pivotal Phase 2 study (KEYNOTE-002) showed KEYTRUDA (pembrolizumab), the companys anti-PD-1 therapy, substantially improved the primary endpoint of progression-free survival (PFS, as assessed by RECIST 1.1, independent central review) (HR 0.57 and 0.50 for 2 mg/kg and 10 mg/kg every three week doses, respectively), compared to chemotherapy (P<0.0001 for both comparisons) Language: English Contact: MerckMedia:Lainie Keller, 908-236-5036Claire Mulhearn, 908-236-1118orInvestor:Joseph Romanelli, 908-423-5185Justin Holko, 908-423-5088 Ticker Slug: Ticker: MRK Exchange: NYSE read more

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SEC investigating Joy Global's Chinese acquisition

2014-11-08 05:02:01| Industrial Machines - Topix.net

The U.S. Securities and Exchange Commission is investigating Milwaukee-based Joy Global's accounting around its purchase of a Chinese-based company it acquired in 2011. The U.S. Securities and Exchange Commission has served a subpoena on Joy Global Inc. to find out more about its acquisition of International Mining Machinery Holdings Ltd., according to a press release by Joy Global.

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New Studies Investigating the Use of KEYTRUDA (pembrolizumab), Mercks Anti-PD-1 Therapy, in Advanced Melanoma Compared to Chemotherapy, in Classical Hodgkin Lymphoma and in Triple Negative Breast Cancer, to be Presented for the First Time

2014-11-06 15:08:00| Merck.com - Corporate News

Dateline City: WHITEHOUSE STATION, N.J. By Year End, Data on KEYTRUDA in Seven Tumor Types Will Have Been Presented WHITEHOUSE STATION, N.J.--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, announced today that in November and December, data will be presented for the first time investigating the use of KEYTRUDA (pembrolizumab) the companys anti-PD-1 therapy in advanced melanoma in comparison to chemotherapy, and in relapsed/refractory classical Hodgkin Lymphoma (cHL) as well as advanced triple negative breast cancer (TNBC). Language: English Contact: MerckMedia:Pamela Eisele, 267-305-3558Claire Mulhearn, 908-236-1118orInvestor:Joseph Romanelli, 908-423-5185Justin Holko, 908-423-5088 Ticker Slug: Ticker: MRK Exchange: NYSE read more

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Investigating AMD Mantles superb multi-GPU scaling in Civilization: Beyond Earth

2014-10-27 16:32:32| Extremetech

AMD is claiming that Mantle can offer a unique and potent improvement to Civilization: Beyond Earth. We take that concept for a test drive.

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Police investigating white powder found on train in Penn Station

2014-10-14 13:15:48| Railroads - Topix.net

The NYPD and the Fire Department began investigating a suspicious white powder found on a train in New York's Penn Station on Monday night, authorities said. The powder was found on a New Jersey Transit train in the station around 6 p.m., an Amtrak spokesman said.

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