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FDA Approves KEYTRUDA (pembrolizumab) for the Treatment of Patients with Metastatic Non-Small Cell Lung Cancer Whose Tumors Express PD-L1 with Disease Progression On or After Platinum-Containing Chemotherapy

2015-10-02 20:49:00| Merck.com - Product News

Dateline City: KENILWORTH, N.J. Patients with EGFR or ALK Genomic Tumor Aberrations Should Have Disease Progression on FDA-Approved Therapy for These Aberrations Prior to Receiving KEYTRUDA KENILWORTH, N.J.--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved KEYTRUDA (pembrolizumab) monotherapy, the companys anti-PD-1 (programmed death receptor-1) therapy, at a dose of 2 mg/kg every three weeks, for the treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors express PD-L1 as determined by an FDA-approved test and who have disease progression on or after platinum-containing chemotherapy. Language: English Contact: MerckMedia Contacts:Pamela Eisele, 267-305-3558Courtney Ronaldo, 908-236-1108orInvestor Contacts:Teri Loxam, 908-740-1986Justin Holko, 908-740-1879 Ticker Slug: Ticker: MRK Exchange: NYSE read more

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Pfizer's Ibrance drug slows progression of breast cancer

2015-05-30 19:03:57| Biotech - Topix.net

CHICAGO: A Phase III trial of Pfizer Inc's drug Ibrance showed that, in combination with hormone therapy, the drug more than doubled the duration of disease control for women with the most common type of breast cancer. At the time of an interim analysis, patients given Ibrance in combination with AstraZeneca Plc's Faslodex , a widely used treatment to block estrogen, lived an average of 9.2 months before their cancer worsened.

Tags: drug cancer breast progression

 
 

KEYTRUDA (pembrolizumab), Mercks Anti-PD-1 Therapy, Demonstrates Superior Survival, Progression Free Survival and Overall Response Rate Compared to Ipilimumab an Anti-CTLA-4 Therapy...

2015-04-19 14:30:00| Merck.com - Product News

Dateline City: PHILADELPHIA ...in a Phase 3 Study of Patients with Advanced Melanoma Data from KEYNOTE-006 Study Presented at AACR Annual Meeting and Published in the New England Journal of Medicine Merck Plans to Submit sBLA for First-Line Indication in Advanced Melanoma in Mid-2015 PHILADELPHIA--(BUSINESS WIRE)--Merck (NYSE:MRK), known as MSD outside the United States and Canada, today announced results from the randomized, pivotal Phase 3 study, KEYNOTE-006, in the treatment of unresectable advanced melanoma. In the study, KEYTRUDA (pembrolizumab) was statistically superior to ipilimumab for progression-free survival (PFS), overall survival (OS), and overall response rate (ORR). On March 24, 2015, Merck announced that KEYNOTE-006 would be stopped early based on these data (link). Language: English Contact: MerckMedia:Pamela Eisele, 267-305-3558orClaire Mulhearn, 908-236-1118orInvestors:Joseph Romanelli, 908-740-1986orJustin Holko, 908-740-1879 Ticker Slug: Ticker: MRK Exchange: NYSE read more

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Lumitec Launches Progression Innovation Boat

2015-03-06 11:31:13| Industrial Newsroom - All News for Today

Industry Leader Unveils Latest in Connected-Boat Technologies Delray Beach, Fla. Lumitec, an engineering and design firm focused on the conceptualization, development and manufacture of high-quality extreme environment LED lighting, launched today its groundbreaking innovation boat, Progression. Showcasing new...

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Modelling of the Progression of an Offshore Hydrocarbon Release Accident

2015-01-06 18:07:00| Hydrocarbons Technology

Quantitative Risk Analysis remains one of the main tools available to understand the different consequences that might follow activities on offshore installations.

Tags: release accident progression offshore

 

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