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ALLY Trial Demonstrates High Cure Rates for Investigational...

2014-11-08 23:40:51| Biotech - Topix.net

Bristol-Myers Squibb Company today announced late-breaking data from the landmark ALLY Trial investigating a ribavirin-free 12-week regimen of daclatasvir in combination with sofosbuvir in genotype 3 hepatitis C patients, a patient population that has emerged as one of the most difficult to treat. The results of the study, which showed sustained virologic response 12 weeks after treatment in 90% of treatment-nai 1 2ve and 86% of treatment-experienced patients, will be presented at The Liver Meeting 2014, the Annual Meeting of The American Association for the Study of Liver Diseases , in Boston, MA, November 7 - 11. "Both treatment nai 1 2ve and treatment experienced patients in the ALLY-3 study achieved high SVR rates.

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General Motors Goes On Trial In January 2016

2014-11-07 17:11:06| Automakers - Topix.net

This is The Morning Shift, our one-stop daily roundup of all the auto news that's actually important - all in one place every weekday morning. Or, you could spend all day waiting for other sites to parse it out to you one story at a time.

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Changes to late-stage breast cancer trial sends shares of Celldex plunging

2014-11-06 01:48:08| Biotech - Topix.net

It wasn't the financial picture at Celldex Therapeutics that sent investors running today. Rather, it was the news that a trial of one its two lead cancer drugs will last longer than hoped that sent its shares down 20 percent as of 2 p.m. today.

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Dyax Corp. Announces Expansion Of Phase 1b Clinical Trial For DX-2930

2014-11-05 07:17:01| drugdiscoveryonline Home Page

Dyax Corp. recently announced the expansion of its ongoing Phase 1b clinical trial evaluating DX-2930 to include additional patients and dosing cohorts

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Ironwood Pharmaceuticals Initiates Phase III Trial Of 72 mcg Linaclotide In Adult Patients With Chronic Idiopathic Constipation

2014-11-05 05:57:43| drugdiscoveryonline Home Page

Ironwood Pharmaceuticals, Inc. announced recently the initiation of a Phase III clinical trial in the U.S. evaluating a 72 mcg capsule of linaclotide to be taken once per day for the treatment of adults suffering from chronic idiopathic constipation (CIC)

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