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Gilead combo HIV pill matches Truvada efficacy but safer in trial

2015-09-02 18:18:32| Biotech - Topix.net

REUTERS: Gilead Sciences Inc said on Wednesday its experimental fixed-dose combination treatment for HIV proved as effective in a late-stage study as the company's widely used Truvada combo pill but with significantly less loss of bone mineral density and kidney function. The company has already sought U.S. and European marketing approval for the new combo pill nicknamed F/TAF, which is meant to be a safer replacement for Truvada, a cornerstone of HIV treatment that has been associated with slight declines in bone mineral density and kidney function.

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Highland Therapeutics Announces Initiation Of Second Pivotal Trial Of HLD-200 In Pediatric ADHD Patients

2015-09-02 07:45:41| drugdiscoveryonline News Articles

Highland Therapeutics Inc. (“Highland”) announced recently that its wholly owned subsidiary, Ironshore Pharmaceuticals & Development, Inc. (“Ironshore”), has dosed the first patient in the second of two pivotal studies of HLD-200

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Finerenone Cuts Deaths in Mid-Stage Trial

2015-09-01 05:16:57| Chemicals - Topix.net

Promising data from an exploratory phase IIb trial of finerenone , an oral, nonsteroidal mineralocorticoid receptor antagonist , have been presented at the European Society of Cardiology Congress 2015 in London. The ARTS-HF study investigated the effects of different dosages of finerenone compared with eplerenone in patients with worsening chronic heart failure with a reduced ejection fraction as well as type-2 diabetes mellitus and/or chronic kidney disease.

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Chesapeake man who represented himself at trial convicted of murder

2015-09-01 01:07:30| Paper - Topix.net

That's how much time a jury has recommended a Chesapeake man serve for stabbing his wife to death in 2010 in front of her daughter and numerous witnesses. Johnson, 55, represented himself during the six-day trial in Circuit Court.

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BT starts G.fast trial in Huntingdon

2015-08-25 09:57:00| Telecompaper Headlines

(Telecompaper) BT Openreach has announced the start of its G.fast trial in Huntingdon. Some 2,000 homes and premises will test the up to 330 Mbps service in the coming weeks. The trial will run for 6-9 months, allowing Openreach, the eight communications providers trialing the technology and BT's R&D division to assess the technical performance across a large footprint. Various methods of deployment will be used to provide insight into how the technology can be used on a day-to-day basis, including how usage might grow over time. If the G.fast trials in Hutingdon, Gosforth and Swansea prove successful, Openreach aims to start deploying G.fast in 2016/17 alongside its FttC and FttP services. The company believes that G.fast will enable it to make speeds of a few hundred megabits per second available to millions of homes by 2020 and deliver up to 500 Mbps to most of the UK within a decade as the technology is developed further.

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