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Hurricane ARTHUR Public Advisory Number 12A

2014-07-04 01:00:22| National Hurricane Center (Atlantic)

Issued at 700 PM EDT THU JUL 03 2014 000 WTNT31 KNHC 032300 TCPAT1 BULLETIN HURRICANE ARTHUR INTERMEDIATE ADVISORY NUMBER 12A NWS NATIONAL HURRICANE CENTER MIAMI FL AL012014 700 PM EDT THU JUL 03 2014 ...EYEWALL OF ARTHUR JUST EAST OF CAPE FEAR... SUMMARY OF 700 PM EDT...2300 UTC...INFORMATION ---------------------------------------------- LOCATION...33.8N 77.4W ABOUT 35 MI...55 KM E OF CAPE FEAR NORTH CAROLINA ABOUT 140 MI...225 KM SW OF CAPE HATTERAS NORTH CAROLINA MAXIMUM SUSTAINED WINDS...90 MPH...150 KM/H PRESENT MOVEMENT...NNE OR 30 DEGREES AT 15 MPH...24 KM/H MINIMUM CENTRAL PRESSURE...977 MB...28.85 INCHES WATCHES AND WARNINGS -------------------- CHANGES WITH THIS ADVISORY... NONE. SUMMARY OF WATCHES AND WARNINGS IN EFFECT... A HURRICANE WARNING IS IN EFFECT FOR... * SURF CITY NORTH CAROLINA TO THE NORTH CAROLINA/VIRGINIA BORDER * PAMLICO SOUND * EASTERN ALBEMARLE SOUND A HURRICANE WATCH IS IN EFFECT FOR... * LITTLE RIVER INLET TO SOUTH OF SURF CITY A TROPICAL STORM WARNING IS IN EFFECT FOR... * SOUTH SANTEE RIVER SOUTH CAROLINA TO SOUTH OF SURF CITY * THE NORTH CAROLINA/VIRGINIA BORDER TO CAPE CHARLES LIGHT VIRGINIA...INCLUDING THE MOUTH OF THE CHESAPEAKE BAY * WESTERN ALBEMARLE SOUND * NANTUCKET * CAPE COD FROM PROVINCETOWN TO CHATHAM A TROPICAL STORM WATCH IS IN EFFECT FOR... * NOVA SCOTIA FROM PORT MAITLAND TO POINT ACONI A HURRICANE WARNING MEANS THAT HURRICANE CONDITIONS ARE EXPECTED SOMEWHERE WITHIN THE WARNING AREA. PREPARATIONS TO PROTECT LIFE AND PROPERTY SHOULD HAVE ALREADY BEEN COMPLETED. A HURRICANE WATCH MEANS THAT HURRICANE CONDITIONS ARE POSSIBLE WITHIN THE WATCH AREA. ANY UNEXPECTED DEVIATION OF THE TRACK TO THE LEFT...OR AN EXPANSION OF HURRICANE-FORCE WINDS INTO THE NORTHWEST QUADRANT OF THE STORM...WOULD BRING HURRICANE-FORCE WINDS TO THE COAST IN THE WATCH AREA. A TROPICAL STORM WARNING MEANS THAT TROPICAL STORM CONDITIONS ARE EXPECTED SOMEWHERE WITHIN THE WARNING AREA. INTERESTS ELSEWHERE IN COASTAL PORTIONS OF NEW ENGLAND...NOVA SCOTIA...AND NEWFOUNDLAND SHOULD MONITOR THE PROGRESS OF ARTHUR. FOR STORM INFORMATION SPECIFIC TO YOUR AREA IN THE UNITED STATES...INCLUDING POSSIBLE INLAND WATCHES AND WARNINGS...PLEASE MONITOR PRODUCTS ISSUED BY YOUR LOCAL NATIONAL WEATHER SERVICE FORECAST OFFICE. FOR STORM INFORMATION SPECIFIC TO YOUR AREA OUTSIDE THE UNITED STATES...PLEASE MONITOR PRODUCTS ISSUED BY YOUR NATIONAL METEOROLOGICAL SERVICE. DISCUSSION AND 48-HOUR OUTLOOK ------------------------------ AT 700 PM EDT...2300 UTC...THE CENTER OF HURRICANE ARTHUR WAS LOCATED NEAR LATITUDE 33.8 NORTH...LONGITUDE 77.4 WEST. ARTHUR IS MOVING TOWARD THE NORTH-NORTHEAST NEAR 15 MPH...24 KM/H. A TURN TOWARD THE NORTHEAST WITH AN INCREASE IN FORWARD SPEED IS EXPECTED TONIGHT...FOLLOWED BY A FURTHER INCREASE IN FORWARD SPEED ON FRIDAY. ON THE FORECAST TRACK...THE CORE OF ARTHUR IS EXPECTED TO PASS NEAR OR OVER THE COAST OF NORTH CAROLINA AND THE OUTER BANKS TONIGHT. THE CENTER OF ARTHUR IS FORECAST TO PASS EAST OF THE MID-ALANTIC COAST FRIDAY AND APPROACH NOVA SCOTIA FRIDAY NIGHT. MAXIMUM SUSTAINED WINDS REMAIN NEAR 90 MPH...150 KM/H...WITH HIGHER GUSTS. SOME STRENGTHENING IS FORECAST DURING THE NEXT 24 HOURS... AND ARTHUR IS EXPECTED TO BE A CATEGORY TWO HURRICANE WHEN IT PASSES OVER OR NEAR THE NORTH CAROLINA COAST. ARTHUR IS EXPECTED TO BEGIN WEAKEN FRIDAY NIGHT AND IS FORECAST TO BECOME A POST-TROPICAL CYCLONE SATURDAY. HURRICANE FORCE WINDS EXTEND OUTWARD UP TO 35 MILES...55 KM...FROM THE CENTER...AND TROPICAL STORM FORCE WINDS EXTEND OUTWARD UP TO 150 MILES...240 KM. A BUOY OPERATED BY THE NORTH CAROLINA COASTAL OCEAN RESEARCH AND MONITORING PROGRAM HAS JUST REPORTED SUSTAINED WINDS OF 49 MPH...79 KM/H...AND A WIND GUST OF 55 MPH...88 KM/H. THE LATEST MINIMUM CENTRAL PRESSURE MEASURED BY A NOAA HURRICANE HUNTER AIRCRAFT WAS 977 MB...28.85 INCHES. HAZARDS AFFECTING LAND ---------------------- WIND...TROPICAL STORM CONDITIONS ARE EXPECTED TO REACH PORTIONS OF THE WARNING AREA WITHIN THE NEXT FEW HOURS AND SPREAD NORTHWARD THROUGH THE TROPICAL STORM AND HURRICANE WARNING AREAS THIS EVENING AND TONIGHT. HURRICANE CONDITIONS ARE EXPECTED WITHIN PORTIONS OF THE HURRICANE WARNING AREA BY TONIGHT. HURRICANE-FORCE WINDS ARE POSSIBLE IN THE HURRICANE WATCH AREA BEGINNING THIS EVENING. ANY UNEXPECTED DEVIATION OF THE TRACK TO THE LEFT...OR AN EXPANSION OF HURRICANE-FORCE WINDS INTO THE NORTHWEST QUADRANT OF THE STORM...WOULD BRING HURRICANE-FORCE WINDS TO THE COAST IN THE HURRICANE WATCH AREA. STORM SURGE...THE COMBINATION OF A DANGEROUS STORM SURGE AND THE TIDE WILL CAUSE NORMALLY DRY AREAS NEAR THE COAST TO BE FLOODED BY RISING WATERS. THE WATER COULD REACH THE FOLLOWING HEIGHTS ABOVE GROUND IF THE PEAK SURGE OCCURS AT THE TIME OF HIGH TIDE... NORTH CAROLINA WITHIN THE HURRICANE WARNING AREA...3 TO 5 FT PAMLICO AND ALBEMARLE SOUNDS...2 TO 4 FT SOUTHERN NORTH CAROLINA AND NORTHEASTERN SOUTH CAROLINA...1 TO 3 FT EXTREME SOUTHEASTERN VIRGINIA...1 TO 3 FT COASTAL FLOODING IS ALSO POSSIBLE ALONG CAPE COD. THE HIGHEST WATER WILL OCCUR ALONG THE IMMEDIATE COAST IN AREAS OF ONSHORE FLOW. THE SURGE WILL BE ACCOMPANIED BY LARGE AND DAMAGING WAVES. SURGE-RELATED FLOODING DEPENDS ON THE RELATIVE TIMING OF THE SURGE AND THE TIDAL CYCLE...AND CAN VARY GREATLY OVER SHORT DISTANCES. FOR INFORMATION SPECIFIC TO YOUR AREA...PLEASE SEE PRODUCTS ISSUED BY YOUR LOCAL NATIONAL WEATHER SERVICE OFFICE AND THE NEW EXPERIMENTAL POTENTIAL STORM SURGE FLOODING MAP FOR MORE DETAILS. RAINFALL...RAINFALL ACCUMULATIONS OF 4 TO 6 INCHES...WITH ISOLATED MAXIMUM AMOUNTS OF 8 INCHES...ARE EXPECTED OVER COASTAL AREAS OF NORTH CAROLINA THROUGH FRIDAY. RAINFALL ACCUMULATIONS OF 1 TO 2 INCHES ARE POSSIBLE ALONG THE UPPER COAST OF SOUTH CAROLINA. RAINFALL ACCUMULATIONS OF 2 TO 4 INCHES ARE EXPECTED OVER PORTIONS OF EASTERN MASSACHUSETTS AND RHODE ISLAND. TORNADOES...ISOLATED TORNADOES ARE POSSIBLE OVER PORTIONS OF COASTAL NORTH CAROLINA THROUGH FRIDAY MORNING. SURF...SWELLS GENERATED BY ARTHUR ARE AFFECTING AREAS FROM THE COAST OF GEORGIA NORTHWARD TO NORTH CAROLINA. THESE SWELLS ARE EXPECTED TO CAUSE LIFE-THREATENING SURF AND RIP CURRENTS. FOR MORE INFORMATION...PLEASE MONITOR PRODUCTS ISSUED BY YOUR LOCAL NATIONAL WEATHER SERVICE FORECAST OFFICE. NEXT ADVISORY ------------- NEXT INTERMEDIATE ADVISORY...900 PM EDT. NEXT COMPLETE ADVISORY...1100 PM EDT. $$ FORECASTER BEVEN

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Clovis Oncology reports lucitanib Phase 1/2a monotherapy study results at ASCO

2014-05-31 19:24:01| Logistics - Topix.net

Clovis Oncology today announced results from an ongoing Phase 1/2a monotherapy study evaluating lucitanib, the Company's novel, potent inhibitor of the tyrosine kinase activity of fibroblast growth factor receptors 1 through 3 , vascular endothelial growth factor receptors 1 through 3 and platelet-derived growth factor receptors alpha and beta .

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Tropical Storm SONIA Public Advisory Number 12A

2013-11-04 06:56:27| National Hurricane Center (East Pacific)

Issued at 1000 PM PST SUN NOV 03 2013 000 WTPZ33 KNHC 040556 TCPEP3 BULLETIN TROPICAL STORM SONIA INTERMEDIATE ADVISORY NUMBER 12A NWS NATIONAL HURRICANE CENTER MIAMI FL EP182013 1000 PM PST SUN NOV 03 2013 ...SONIA APPROACHING THE COAST OF SINALOA MEXICO... SUMMARY OF 1000 PM PST...0600 UTC...INFORMATION ----------------------------------------------- LOCATION...24.0N 107.8W ABOUT 60 MI...95 KM SSW OF CULIACAN MEXICO ABOUT 115 MI...180 KM WNW OF MAZATLAN MEXICO MAXIMUM SUSTAINED WINDS...40 MPH...65 KM/H PRESENT MOVEMENT...NNE OR 30 DEGREES AT 18 MPH...30 KM/H MINIMUM CENTRAL PRESSURE...1004 MB...29.65 INCHES WATCHES AND WARNINGS -------------------- CHANGES WITH THIS ADVISORY... NONE. SUMMARY OF WATCHES AND WARNINGS IN EFFECT... A TROPICAL STORM WARNING IS IN EFFECT FOR... * MAZATLAN TO ALTATA A TROPICAL STORM WATCH IS IN EFFECT FOR... * NORTH OF ALTATA TO TOPOLOBAMPO INTERESTS ELSEWHERE IN WEST-CENTRAL MAINLAND MEXICO SHOULD MONITOR THE PROGRESS OF SONIA. FOR STORM INFORMATION SPECIFIC TO YOUR AREA...PLEASE MONITOR PRODUCTS ISSUED BY YOUR NATIONAL METEOROLOGICAL SERVICE. DISCUSSION AND 48-HOUR OUTLOOK ------------------------------ AT 1000 PM PST...0600 UTC...THE CENTER OF TROPICAL STORM SONIA WAS LOCATED NEAR LATITUDE 24.0 NORTH...LONGITUDE 107.8 WEST. SONIA IS MOVING TOWARD THE NORTH-NORTHEAST NEAR 18 MPH...30 KM/H...AND THIS MOTION IS EXPECTED TO CONTINUE ON MONDAY. ON THE FORECAST TRACK...THE CENTER OF SONIA SHOULD REACH THE COAST OF MAINLAND MEXICO WITHIN THE WARNING AREA DURING THE NEXT FEW HOURS. MAXIMUM SUSTAINED WINDS ARE NEAR 40 MPH...65 KM/H...WITH HIGHER GUSTS. RAPID WEAKENING IS EXPECTED AFTER SONIA MOVES INLAND DURING THE NEXT FEW HOURS. SONIA IS FORECAST TO DISSIPATE OVER MEXICO ON MONDAY AFTERNOON. TROPICAL STORM FORCE WINDS EXTEND OUTWARD UP TO 35 MILES...55 KM FROM THE CENTER. THE ESTIMATED MINIMUM CENTRAL PRESSURE IS 1004 MB...29.65 INCHES. HAZARDS AFFECTING LAND ---------------------- WIND...TROPICAL STORM CONDITIONS ARE EXPECTED IN THE WARNING AREA AND POSSIBLE IN THE WATCH AREA DURING THE NEXT FEW HOURS. RAINFALL...SONIA IS EXPECTED TO PRODUCE TOTAL RAIN ACCUMULATIONS OF 3 TO 6 INCHES...WITH ISOLATED MAXIMUM AMOUNTS OF 10 INCHES...IN PORTIONS OF THE MEXICAN STATES OF SINALOA...WESTERN DURANGO...AND SOUTHERN CHIHUAHUA. THESE RAINS MAY PRODUCE LIFE-THREATENING FLASH FLOODS AND MUD SLIDES. NEXT ADVISORY ------------- NEXT COMPLETE ADVISORY...100 AM PST. $$ FORECASTER BERG

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Hurricane RAYMOND Public Advisory Number 12A

2013-10-23 01:45:38| Tropical Depression LIDIA

...RAYMOND STILL PARKED OFF THE COAST OF SOUTHERN MEXICO... Location: 16.3°N 101.9°W Max sustained: 75 mph Moving: Stationary Min pressure: 987 mb Issued at 500 PM PDT TUE OCT 22 2013

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