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Depression Treatments Inspired By Club Drug Move Ahead In Tests
2015-05-28 23:51:25| Biotech - Topix.net
"We're getting closer and closer to having really, truly next-generation treatments that are better and quicker than existing ones," says Dr. Carlos Zarate , a researcher at the National Institute of Mental Health. The new drugs are based on the anesthetic ketamine, which is also a popular club drug known as Special K. Unlike current antidepressants, which can take weeks to work, ketamine-like drugs have an immediate effect.
Tropical Depression ONE-E Graphics
2015-05-28 11:03:50| National Hurricane Center (East Pacific)
5-Day Uncertainty Track last updated Thu, 28 May 2015 08:43:34 GMT Wind Speed Probabilities last updated Thu, 28 May 2015 09:03:45 GMT
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Tropical Depression ONE-E Forecast Discussion Number 1
2015-05-28 10:42:38| National Hurricane Center (East Pacific)
Issued at 300 AM MDT THU MAY 28 2015 000 WTPZ41 KNHC 280842 TCDEP1 TROPICAL DEPRESSION ONE-E DISCUSSION NUMBER 1 NWS NATIONAL HURRICANE CENTER MIAMI FL EP012015 300 AM MDT THU MAY 28 2015 Deep convection has become increasingly consolidated and organized in association with an area of low pressure located well to the southwest of the coast of Mexico. Enough convective banding has formed to yield Dvorak estimates of T2.0/30 kt from TAFB and T1.5/25 kt from SAB, and a 0459 UTC ASCAT-B pass showed maximum winds near 30 kt. The ASCAT data also showed that a center of circulation appeared sufficiently well defined, allowing the designation of the low as a 30-kt tropical depression at this time. The depression lies to the south of a mid-level ridge which extends from central Mexico west-southwestward over the eastern Pacific, and its initial motion is 295/13 kt. Global model fields show that the ridge should remain firmly in place, especially to the northwest of the depression, during the next several days. This should force the cyclone to slow down considerably and move north-northwestward from days 2 through 5. There is good agreement among the track models during the first 3 days of the forecast. By days 4 and 5, however, there is more uncertainty with the GFDL and HWRF models showing a northward motion while the GFS and ECMWF show a northwestward motion. The NHC track forecast currently lies closest to the GFS model and the TVCE multi-model consensus. Regardless of the exact track, the cyclone is expected to stay well to the southwest of Mexico during the entire forecast period. Relatively low shear and warmer-than-normal sea surface temperatures should support intensification during the next 3 days or so. Of the intensity guidance, the SHIPS model is the most aggressive, making the cyclone a hurricane by 36 hours with a peak intensity near 90 kt in 2-3 days. The official intensity forecast isn't quite that aggressive, but it does lie slightly above the ICON intensity consensus. Rapid intensification isn't out of the question, and in fact the RI guidance suggests that it may be likely during the next 24 hours. In light of that, some upward adjustment to the official forecast may be needed in subsequent advisories. Weakening should begin by day 4 once the cyclone reaches colder water. Note that beginning this year, Tropical Cyclone Public Advisories, Discussions, and Updates for the eastern North Pacific will now use different time zones depending on the cyclone's current location, as follows: Central Time: east of 106.0W Mountain Time: 106.0W to 114.9W Pacific Time: 115.0W westward FORECAST POSITIONS AND MAX WINDS INIT 28/0900Z 11.0N 110.4W 30 KT 35 MPH 12H 28/1800Z 11.7N 111.5W 40 KT 45 MPH 24H 29/0600Z 12.6N 112.8W 50 KT 60 MPH 36H 29/1800Z 13.4N 113.5W 60 KT 70 MPH 48H 30/0600Z 14.2N 114.0W 70 KT 80 MPH 72H 31/0600Z 16.0N 115.0W 80 KT 90 MPH 96H 01/0600Z 17.5N 116.0W 70 KT 80 MPH 120H 02/0600Z 19.0N 117.0W 60 KT 70 MPH $$ Forecaster Berg
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Summary for Tropical Depression ONE-E (EP1/EP012015)
2015-05-28 10:40:26| National Hurricane Center (East Pacific)
...FIRST TROPICAL DEPRESSION OF THE EASTERN PACIFIC HURRICANE SEASON FORMS WELL SOUTHWEST OF MEXICO... As of 3:00 AM MDT Thu May 28 the center of ONE-E was located near 11.0, -110.4 with movement WNW at 15 mph. The minimum central pressure was 1005 mb with maximum sustained winds of about 35 mph.
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Tropical Depression ONE-E Public Advisory Number 1
2015-05-28 10:40:26| National Hurricane Center (East Pacific)
Issued at 300 AM MDT THU MAY 28 2015 000 WTPZ31 KNHC 280840 TCPEP1 BULLETIN TROPICAL DEPRESSION ONE-E ADVISORY NUMBER 1 NWS NATIONAL HURRICANE CENTER MIAMI FL EP012015 300 AM MDT THU MAY 28 2015 ...FIRST TROPICAL DEPRESSION OF THE EASTERN PACIFIC HURRICANE SEASON FORMS WELL SOUTHWEST OF MEXICO... SUMMARY OF 300 AM MDT...0900 UTC...INFORMATION ---------------------------------------------- LOCATION...11.0N 110.4W ABOUT 685 MI...1105 KM SW OF MANZANILLO MEXICO MAXIMUM SUSTAINED WINDS...35 MPH...55 KM/H PRESENT MOVEMENT...WNW OR 295 DEGREES AT 15 MPH...24 KM/H MINIMUM CENTRAL PRESSURE...1005 MB...29.68 INCHES WATCHES AND WARNINGS -------------------- There are no coastal watches or warnings in effect. DISCUSSION AND 48-HOUR OUTLOOK ------------------------------ At 300 AM MDT (0900 UTC), the center of Tropical Depression One-E was located near latitude 11.0 North, longitude 110.4 West. The depression is moving toward the west-northwest near 15 mph (24 km/h), but a decrease in forward speed is expected to begin later today. The depression should turn toward the northwest by tonight and the north-northwest by Friday night. Maximum sustained winds are near 35 mph (55 km/h) with higher gusts. Strengthening is forecast during the next 48 hours. The depression is expected to become a tropical storm later this morning and could become a hurricane by late Friday. The estimated minimum central pressure is 1005 mb (29.68 inches). HAZARDS AFFECTING LAND ---------------------- None NEXT ADVISORY ------------- Next complete advisory at 900 AM MDT. $$ Forecaster Berg
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